FUB-AMB is an indazole-based synthetic cannabinoid that is a potent agonist of the CB1 receptor. Another synonym used for FUB-AMB in the expert circles is AMB-FUBINACA , and simple chemical formula of the substance is summed up as C21H22FN3O3 .
FUB-AMB is official designation in the IUPAC system is defined as methyl (1-(4-fluorobenzyl)-1H-indazole-3-carbonyl)-L-valinate, with the molecular weight determined to be 383.41 g/mol.
FUB-AMB is an analogue of AB-FUBINACA, a potent synthetic cannabinoid first synthesized by Pfizer. AB-FUBINACA exhibits a strong affinity (Ki =0.9 nM) for the CB1 receptor. The primary amide moiety in the L-valinamide side chain in AB-FUBINACA is replaced with a methyl ester in FUB-AMB.
Despite the lack of information on how a chemical substance like this impacts human subjects, many individuals have started to buy FUB-AMB for use as a recreational designer drug. The purpose of this in many users is because they hope to achieve euphoric experiences similar or greater than those they might achieve with more commonly obtained prescription medications or over the counter substances. Some might also use this type of chemical as a recreational drug in the hopes of achieving these results without the negative side effects that can also be brought on by those more common medications.
Some more technical information on this compound includes:
Formal Name: methyl (1-(4-fluorobenzyl)-1H-indazole-3-carbonyl)-L-valinate
Formula Weight: 383.4
Purity: Greater than or equal to 98%
Formulation: A solution in acetronitrile
Stability: Typically no less than two years worth of stability
What is it used for?
Pfizer was working on developing a synthetic cannabinoid to treat pain in cancer patients, as synthetic
cannabinoids may be more likely to ease pain without the effects of THC (i.e., producing a high in the user).
During the clinical trials, Pfizer discontinued their research into properties of the drug. Currently, there are no
approved medical uses in humans for FUB-AMB or its related compounds.
Synthetic cannabinoids are the most rapidly growing class of designer recreational drugs. With this rise in new
cannabinoids, users may be unaware of what they are consuming. Declared ingredients and potency of these
products are usually inaccurate or false and additional ingredients like caffeine, nicotine, vitamin E, and
synthetic opioids have been found within synthetic cannabinoids. FUB-AMB is anywhere from 30 to 500
times more potent than THC and 50 times as potent as older variations of synthetic marijuana, like JWH-18.
Inconsistency among ingredients between products creates wide variation in the strength and side effects